A United Launch Alliance (ULA) Atlas V rocket launched Boeing’s Crew Space Transportation (CST)-100 Starliner spacecraft with two NASA astronauts, Barry “Butch” Wilmore and Sunita "Suni" Williams on the Crew Flight Test (CFT) from Cape Canaveral Space Force Station's Space Launch Complex 41 at 10:52 a.m. on 5 June 2024. Following separation from the Atlas V rocket, Starliner's engines will burn taking it the rest of the way to orbit and on to the International Space Station, returning approximately eight days later to a landing in the Western United States. CFT is ULA's first human launch using a Starliner spacecraft named "Calypso" by Sunita Williams in 2019.

CFT is the final test to demonstrate the full end-of-end capabilities of the Starliner system to deliver crews to and from the space station as part of NASA's Commercial Crew Program. Following a successful test flight with astronauts, NASA will begin the final process of certifying the Starliner for long-duration crew rotation missions to the space station.